Preheat the air fryer to 400 degrees. Meanwhile, setup the egg wash and dredge. In one shallow dish, add the egg and whisk it together with the water. In another shallow dish, add the panko breadcrumbs, garlic powder, paprika, salt and pepper. Mix the panko mixture together so the seasonings spread evenly.
With one hand, roll a piece of salmon in the egg wash and lay it in the panko mixture. With the other hand, roll the salmon in the panko. Lay on a plate and repeat with the remaining salmon.
Spray the bottom of the air fryer tray with cooking spray. Lay out the breaded salmon, spray the tops with cooking spray and cook for 10 minutes. Serve warm.